![]() These are the first cases of EVD confirmed in Guinea since the 2014–2016 West Africa outbreak, the largest in history, was declared over. On February 14, 2021, the Ministry of Health (MOH) in Guinea announced that cases of Ebola virus disease (EVD) had been confirmed in N’Zérékoré Prefecture, a forested rural region in southeast Guinea. Reported number of deaths and percentage of fatal cases: 12 (52.2%).The outbreak was declared over on May 3, 2021. Sequencing of samples suggests that cases in this outbreak were linked to cases in the area during the 2018–2020 outbreak and likely resulted from persistent infection in a survivor that led to either a relapse or sexual transmission of the virus. North Kivu was previously affected by EVD during the 2018–2020 Ebola outbreak, the largest in DRC’s history, which was declared over on June 25, 2020. On February 7, 2021, the Ministry of Health (MOH) in the Democratic Republic of the Congo (DRC) announced that a case of Ebola virus disease (EVD) had been confirmed in Biena Health Zone, North Kivu Province. Reported number of deaths and percentage of fatal cases: 6 (50%). ![]() This outbreak, the 13 th EVD outbreak in DRC, was declared officially over on December 16, 2021, 42 days after the last confirmed patient was released from treatment. ![]() Sequencing data showed a link to the 2018-2020 outbreak in the same region, suggesting this outbreak was likely caused by a persistent infection in an EVD survivor. Subsequent cases were confirmed in the same health zone and three probable cases were retrospectively identified from September 2021. On October 8, the Ministry of Health in DRC announced an outbreak of EVD in Beni Health Zone, North Kivu Province.
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